Warisan Bencana DuPont: PFAS Bahan Kimia Abadi

Authors

  • Muhammad Lathiful Khuluq Program Studi Ilmu Kelautan Fakultas Perikanan dan Ilmu Kelautan Universitas Brawijaya
  • Muhammad Rafly Haryansyah Program Studi Ilmu Kelautan Fakultas Perikanan dan Ilmu Kelautan Universitas Brawijaya
  • Syarifah Hikmah Julinda Sari Fakultas Perikanan dan Ilmu Kelautan Universitas Brawijaya

DOI:

https://doi.org/10.58954/epj.v5i1.284

Keywords:

PFAS, DuPont, Kesehatan, Lingkungan, Pencemaran

Abstract

Per- dan polifluoroalkil (PFAS), yang dikenal sebagai "bahan kimia abadi," merupakan kelompok kontaminan sintetis yang sangat persisten dan sulit terurai di lingkungan. Penelitian ini mengkaji dampak PFAS, khususnya PFOA dan PFOS, terhadap kesehatan manusia dan lingkungan, serta menguraikan awal mula kesadaran akan bahaya PFAS dari kasus perusahaan DuPont. Studi ini menggunakan metode studi literatur dari berbagai sumber untuk menjelaskan sifat kimia PFAS, cara penyebarannya, serta dampaknya pada kesehatan manusia dan lingkungan. Pada 1950-an, DuPont menggunakan PFOA dalam produksi Teflon.  Pengungkapan oleh Rob Bilott pada 1999 menjadi titik balik penting yang membuka tabir bahaya PFAS setelah ditemukan pencemaran air minum yang mempengaruhi penduduk di Parkersburg, AS. Pencemaran PFAS berdampak terhadap kesehatan manusia dan lingkungan sehingga pengendaliannya memerlukan peran sektor pemerintah, industri dan masyarakat.

References

Alukkal, C. R., Modiri, M., Ruiz, R. A., Choi, Y. J., & Lee, L. S. (2025). Evaluation of PFAS extraction and analysis methods for biosolids. Talanta, 286(October 2024), 127485. https://doi.org/10.1016/j.talanta.2024.127485

Bartell, S. M., & Vieira, V. M. (2021). Critical review on PFOA, kidney cancer, and testicular cancer. Journal of the Air and Waste Management Association, 71(6), 663–679. https://doi.org/10.1080/10962247.2021.1909668

Bilela, L. L., Matijošytė, I., Krutkevičius, J., Alexandrino, D. A. M., Safarik, I., Burlakovs, J., Gaudêncio, S. P., & Carvalho, M. F. (2023). Impact of per- and polyfluorinated alkyl substances (PFAS) on the marine environment: Raising awareness, challenges, legislation, and mitigation approaches under the One Health concept. Marine Pollution Bulletin, 194(July). https://doi.org/10.1016/j.marpolbul.2023.115309

Blum, A. (2015). The Madrid Statement on Poly- and Perfluoroalkyl Substances (PFASs). Environmental Health Perspectives, 123(5), A107–A111. https://doi.org/10.1021/es201662b.Fei

Chen, C., Fang, Y., Cui, X., & Zhou, D. (2022). Effects of trace PFOA on microbial community and metabolisms: Microbial selectivity, regulations and risks. Water Research, 226(September), 119273. https://doi.org/10.1016/j.watres.2022.119273

Dalsager, L., Christensen, N., Husby, S., Kyhl, H., Nielsen, F., Høst, A., Grandjean, P., & Jensen, T. K. (2016). Association between prenatal exposure to perfluorinated compounds and symptoms of infections at age 1–4 years among 359 children in the Odense Child Cohort. Environment International, 96, 58–64. https://doi.org/10.1016/j.envint.2016.08.026

Dhore, R., & Murthy, G. S. (2021). Per/polyfluoroalkyl substances production, applications and environmental impacts. Bioresource Technology, 341(August), 125808. https://doi.org/10.1016/j.biortech.2021.125808

Di Nisio, A., Pannella, M., Vogiatzis, S., Sut, S., Dall’Acqua, S., Rocca, M. S., Antonini, A., Porzionato, A., De Caro, R., Bortolozzi, M., De Toni, L., & Foresta, C. (2022). Impairment of human dopaminergic neurons at different developmental stages by perfluoro-octanoic acid (PFOA) and differential human brain areas accumulation of perfluoroalkyl chemicals. Environment International, 158(August 2021), 106982. https://doi.org/10.1016/j.envint.2021.106982

Fragki, S., Dirven, H., Fletcher, T., Grasl-Kraupp, B., Bjerve Gützkow, K., Hoogenboom, R., Kersten, S., Lindeman, B., Louisse, J., Peijnenburg, A., Piersma, A. H., Princen, H. M. G., Uhl, M., Westerhout, J., Zeilmaker, M. J., & Luijten, M. (2021). Systemic PFOS and PFOA exposure and disturbed lipid homeostasis in humans: what do we know and what not? Critical Reviews in Toxicology, 51(2), 141–164. https://doi.org/10.1080/10408444.2021.1888073

Gaber, N., Bero, L., & Woodruff, T. J. (2023). The Devil they Knew: Chemical Documents Analysis of Industry Influence on PFAS Science. Annals of Global Health, 89(1), 1–17. https://doi.org/10.5334/aogh.4013

Gómez, V., Torres, M., Karásková, P., Přibylová, P., Klánová, J., & Pozo, K. (2021). Occurrence of perfluoroalkyl substances (PFASs) in marine plastic litter from coastal areas of Central Chile. Marine Pollution Bulletin, 172(August), 1–6. https://doi.org/10.1016/j.marpolbul.2021.112818

Habsy, B. A. (2017). Seni Memehami Penelitian Kuliatatif Dalam Bimbingan Dan Konseling : Studi Literatur. JURKAM: Jurnal Konseling Andi Matappa, 1(2), 90. https://doi.org/10.31100/jurkam.v1i2.56

Haynes, T. (2019). Dark Waters. Focus Features.

Jahnke, A., & Berger, U. (2009). Trace analysis of per- and polyfluorinated alkyl substances in various matrices-How do current methods perform? Journal of Chromatography A, 1216(3), 410–421. https://doi.org/10.1016/j.chroma.2008.08.098

Jian, J. M., Chen, D., Han, F. J., Guo, Y., Zeng, L., Lu, X., & Wang, F. (2018). A short review on human exposure to and tissue distribution of per- and polyfluoroalkyl substances (PFASs). Science of the Total Environment, 636, 1058–1069. https://doi.org/10.1016/j.scitotenv.2018.04.380

Kotthoff, M., Fliedner, A., Rüdel, H., Göckener, B., Bücking, M., Biegel-Engler, A., & Koschorreck, J. (2020). Per- and polyfluoroalkyl substances in the German environment – Levels and patterns in different matrices. Science of the Total Environment, 740, 140116. https://doi.org/10.1016/j.scitotenv.2020.140116

Li, J., Li, X., Zhu, Y., Wang, L., Ren, S., An, R., Zhang, Q., & Wang, G. (2025). The first survey of legacy and emerging per- and polyfluoroalkyl substances (PFAS) in Hulun Lake, China: Occurrence, sources, and environmental impacts. Emerging Contaminants, 11(1), 100431. https://doi.org/10.1016/j.emcon.2024.100431

Li, K., Gao, P., Xiang, P., Zhang, X., Cui, X., & Ma, L. Q. (2017). Molecular mechanisms of PFOA-induced toxicity in animals and humans: Implications for health risks. Environment International, 99, 43–54. https://doi.org/10.1016/j.envint.2016.11.014

Lindawati, S., & Hendri, M. (2016). Penggunaan Metode Deskriptif Kualitatif Untuk Analisis Strategi Pengembangan Kepariwisataan Kota Sibolga Provinsi Sumatera Utara. Seminar Nasional APTIKOM (SEMNASTIKOM), Hotel Lombok Raya Mataram, 833–837.

Liu, Z., Li, X., & Shi, S. (2021). An Ethical Analysis Model to DuPont’s PFOA Event Based on Consequentialism Perspective. Proceedings of the 2021 International Conference on Enterprise Management and Economic Development (ICEMED 2021), 178(Icemed), 143–149. https://doi.org/10.2991/aebmr.k.210601.025

Llorca, M., Schirinzi, G., Martínez, M., Barceló, D., & Farré, M. (2018). Adsorption of perfluoroalkyl substances on microplastics under environmental conditions. Environmental Pollution, 235, 680–691. https://doi.org/10.1016/j.envpol.2017.12.075

Martin, V. St. (2023). ‘Profit Over the Public’s Health’: Study Details Efforts by Makers of Forever Chemicals to Hide Their Harms. Inside Climate News.

Mastrantonio, M., Bai, E., Uccelli, R., Cordiano, V., Screpanti, A., & Crosignani, P. (2018). Drinking water contamination from perfluoroalkyl substances (PFAS): An ecological mortality study in the Veneto Region, Italy. European Journal of Public Health, 28(1), 180–185. https://doi.org/10.1093/eurpub/ckx066

Panieri, E., Baralic, K., Djukic-Cosic, D., Djordjevic, A. B., & Saso, L. (2022). PFAS Molecules: A Major Concern for the Human Health and the Environment. Toxics, 10(2), 1–55. https://doi.org/10.3390/toxics10020044

Podder, A., Sadmani, A. H. M. A., Reinhart, D., Chang, N. Bin, & Goel, R. (2021). Per and poly-fluoroalkyl substances (PFAS) as a contaminant of emerging concern in surface water: A transboundary review of their occurrences and toxicity effects. Journal of Hazardous Materials, 419(June), 126361. https://doi.org/10.1016/j.jhazmat.2021.126361

Post, G. B., Cohn, P. D., & Cooper, K. R. (2012). Perfluorooctanoic acid (PFOA), an emerging drinking water contaminant: A critical review of recent literature. Environmental Research, 116, 93–117. https://doi.org/10.1016/j.envres.2012.03.007

Putri, S., & Ilyas, M. (2021). Diabetes Mellitus Among Workers Exposed to Perfluorooctanoic acid. The Indonesian Journal of Community and Occupational Medicine, 1(2), 107–113. https://doi.org/10.53773/ijcom.v1i2.10.107-13

Rasouli, M., Jalili Ghazizade, M., Nasrabadi, T., & Baghdadi, M. (2025). Occurrence and transport of per- and polyfluoroalkyl substances (PFAS) in the leachate of a municipal solid waste landfill in Tehran, Iran (a Middle-Eastern megacity). Environmental Research, 270(January), 120957. https://doi.org/10.1016/j.envres.2025.120957

Rich, N. (2016). The Lawyer Who Became DuPont’s Worst Nightmare. The New York Times, 1–23.

Sadia, M., Nollen, I., Helmus, R., Ter Laak, T. L., Béen, F., Praetorius, A., & Van Wezel, A. P. (2023). Occurrence, Fate, and Related Health Risks of PFAS in Raw and Produced Drinking Water. Environmental Science and Technology, 57(8), 3062–3074. https://doi.org/10.1021/acs.est.2c06015

Sinclair, G. M., Long, S. M., & Jones, O. A. H. (2020). What are the effects of PFAS exposure at environmentally relevant concentrations? Chemosphere, 258, 127340. https://doi.org/10.1016/j.chemosphere.2020.127340

Skogheim, T. S., Villanger, G. D., Weyde, K. V. F., Engel, S. M., Surén, P., Øie, M. G., Skogan, A. H., Biele, G., Zeiner, P., Øvergaard, K. R., Haug, L. S., Sabaredzovic, A., & Aase, H. (2020). Prenatal exposure to perfluoroalkyl substances and associations with symptoms of attention-deficit/hyperactivity disorder and cognitive functions in preschool children. International Journal of Hygiene and Environmental Health, 223(1), 80–92. https://doi.org/10.1016/j.ijheh.2019.10.003

Sobhani, Z., Fang, C., Naidu, R., & Megharaj, M. (2021). Microplastics as a vector of toxic chemicals in soil: Enhanced uptake of perfluorooctane sulfonate and perfluorooctanoic acid by earthworms through sorption and reproductive toxicity. Environmental Technology and Innovation, 22, 101476. https://doi.org/10.1016/j.eti.2021.101476

Spyrou, A., Vlastos, D., & Antonopoulou, M. (2024). Evidence on the genotoxic and ecotoxic effects of PFOA, PFOS and their mixture on human lymphocytes and bacteria. Environmental Research, 248(December 2023), 118298. https://doi.org/10.1016/j.envres.2024.118298

Squadrone, S., Ciccotelli, V., Prearo, M., Favaro, L., Scanzio, T., Foglini, C., & Abete, M. C. (2015). Perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA): emerging contaminants of increasing concern in fish from Lake Varese, Italy. Environmental Monitoring and Assessment, 187(7). https://doi.org/10.1007/s10661-015-4686-0

Steenland, K., Fletcher, T., & Savitz, D. A. (2010). Epidemiologic evidence on the health effects of perfluorooctanoic acid (PFOA). Environmental Health Perspectives, 118(8), 1100–1108. https://doi.org/10.1289/ehp.0901827

Teaf, C. M., Garber, M. M., Covert, D. J., & Tuovila, B. J. (2019). Perfluorooctanoic Acid (PFOA): Environmental Sources, Chemistry, Toxicology, and Potential Risks. Soil and Sediment Contamination, 28(3), 258–273. https://doi.org/10.1080/15320383.2018.1562420

Wang, F., Shih, K. M., & Li, X. Y. (2015). The partition behavior of perfluorooctanesulfonate (PFOS) and perfluorooctanesulfonamide (FOSA) on microplastics. Chemosphere, 119, 841–847. https://doi.org/10.1016/j.chemosphere.2014.08.047

Wee, S. Y., & Aris, A. Z. (2023). Environmental impacts, exposure pathways, and health effects of PFOA and PFOS. Ecotoxicology and Environmental Safety, 267(July), 115663. https://doi.org/10.1016/j.ecoenv.2023.115663

Xiao, F., Simcik, M. F., Halbach, T. R., & Gulliver, J. S. (2015). Perfluorooctane sulfonate (PFOS) and perfluorooctanoate (PFOA) in soils and groundwater of a U.S. metropolitan area: Migration and implications for human exposure. Water Research, 72, 64–74. https://doi.org/10.1016/j.watres.2014.09.052

Xu, Z., Chen, Y., & Lyu, X. (2024). Particle size and co-presence of PFOA alter the transport of microplastics in saturated natural sediment. Environmental Pollutants and Bioavailability, 36(1). https://doi.org/10.1080/26395940.2024.2308116

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Published

2025-04-05

How to Cite

Muhammad Lathiful Khuluq, Muhammad Rafly Haryansyah, & Sari, S. H. J. (2025). Warisan Bencana DuPont: PFAS Bahan Kimia Abadi. Environmental Pollution Journal, 5(1), 1225–1236. https://doi.org/10.58954/epj.v5i1.284

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